Disproportionate head growth retardation in cystic fibrosis.

Growth and nutritional status in children and adolescents with cystic fibrosis.

BACKGROUND Growth retardation, delayed puberty and malnutrition are frequently observed in children suffering from cystic fibrosis. AIM The aim of this study was to estimate growth and nutritional status in children with cystic fibrosis on the basis of body proportions and body mass index. SUBJECTS AND METHODS Anthropometric data were collected from the medical histories of 62 patients trea...

Investigation of Growth of Microorganisms within the Spacers of Children with Cystic Fibrosis

Background and aim: Cystic fibrosis is a monogenic disorder in several systems. Since spacers used by these patients may be used several times a day, many of them do not know how to wash and use them, so these devices are good places for bacteria to grow. Therefore, this study was performed to identify and determine the relationship between the growth of microorganisms inside spacers and the ef...

Cystic fibrosis growth retardation is not correlated with loss of Cftr in the intestinal epithelium.

Maldigestion due to exocrine pancreatic insufficiency leads to intestinal malabsorption and consequent malnutrition, a mechanism proposed to cause growth retardation associated with cystic fibrosis (CF). However, although enzyme replacement therapy combined with increased caloric intake improves weight gain, the effect on stature is not significant, suggesting that growth retardation has a more...

Prevalence of Cystic Fibrosis Trans-membrane Conductance Regulator Gene common mutations in children with cystic fibrosis in Isfahan, Iran

Background: Cystic fibrosis (CF) is the most common lethal genetic disorder of Cystic Fibrosis Trans-membrane Conductance (CFTR) Regulator gene mutations. We aimed to investigate common mutations in CF patients and to assess its possible relationship with clinical presentations. Materials and Methods: This cross sectional study was conducted on 36 CF patients who were referred to a tertiary ped...

Dysfunction in Cystic Fibrosis Contribute to Alveolar Macrophage Low Levels of Insulin-like Growth Factor-1